The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Jul. 29, 2013
Applicant:
The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);
Assignee:
The Regents of the University of Colorado, a body corporate, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/747 (2006.01); C07C 235/82 (2006.01); C07C 69/21 (2006.01); C07C 69/757 (2006.01); C07D 307/93 (2006.01); C07C 49/755 (2006.01); C07C 62/38 (2006.01);
U.S. Cl.
CPC ...
C07C 49/747 (2013.01); C07C 49/755 (2013.01); C07C 62/38 (2013.01); C07C 69/21 (2013.01); C07C 69/757 (2013.01); C07C 235/82 (2013.01); C07D 307/93 (2013.01); C07C 2102/12 (2013.01);
Abstract
Provided are compounds, compositions and methods for treating Toll-like receptor 1/2 complex (TLRI/2) related inflammatory disorders. Small molecules, based on the benzotropolone scaffold, capable of influencing downstream signaling are disclosed as well as methods of making and modifying these molecules. Also provided are methods for treating a subject for a clinical condition associated with Toll-like receptor complex 1/2 activation, comprising administering to the subject an effective amount of a benzotropolone compound.