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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9517988 B1

PDFFull Text
Date of Patent:
Dec. 13, 2016

Filed:

Nov. 09, 2015

Phenol derivative and preparation method and use in medicine thereof

Applicant:

Sichuan Haisco Pharmaceutical Co., Ltd., Chengdu, CN;

Inventors:

Linlin Qin, Chengdu, CN;

Fangqiong Li, Chengdu, CN;

Shixu Yi, Chengdu, CN;

Huadong Luo, Chengdu, CN;

Xinfeng Luo, Chengdu, CN;

Songlin Wan, Chengdu, CN;

Lei Ren, Chengdu, CN;

Guoliang Liu, Chengdu, CN;

Yonggang Wei, Chengdu, CN;

Jianyu Liu, Chengdu, CN;

Peng Cho Tang, Chengdu, CN;

Assignee:

Sichuan Haisco Pharmaceutical Co., Ltd., Chengdu, CN;

Attorney:

Brinks Gilson & Lione

Primary Examiner:

Sikarl Witherspoon

Int. Cl.
CPC ...
C07C 43/00 (2006.01); C07C 39/00 (2006.01); C07D 213/00 (2006.01); C07F 9/00 (2006.01); C07C 39/17 (2006.01); C07C 39/42 (2006.01); C07C 69/96 (2006.01); C07C 43/21 (2006.01); C07C 43/23 (2006.01); C07C 69/157 (2006.01); C07C 69/24 (2006.01); C07C 69/82 (2006.01); C07D 207/16 (2006.01); C07F 9/6574 (2006.01); C07F 9/09 (2006.01); C07F 9/12 (2006.01); C07F 9/24 (2006.01); C07D 213/80 (2006.01); C07C 271/22 (2006.01); C07C 271/44 (2006.01); C07C 229/08 (2006.01); C07C 229/36 (2006.01); C07C 37/00 (2006.01); C07C 37/62 (2006.01); C07C 41/18 (2006.01); C07C 67/10 (2006.01); C07C 68/00 (2006.01); C07C 69/07 (2006.01); C07C 69/78 (2006.01); C07C 227/04 (2006.01); C07C 269/00 (2006.01); C07D 213/803 (2006.01); C07F 9/06 (2006.01);
U.S. Cl.
CPC ...
C07C 39/17 (2013.01); C07C 37/00 (2013.01); C07C 37/001 (2013.01); C07C 37/62 (2013.01); C07C 39/42 (2013.01); C07C 41/18 (2013.01); C07C 43/21 (2013.01); C07C 43/23 (2013.01); C07C 67/10 (2013.01); C07C 68/00 (2013.01); C07C 69/07 (2013.01); C07C 69/157 (2013.01); C07C 69/24 (2013.01); C07C 69/78 (2013.01); C07C 69/82 (2013.01); C07C 69/96 (2013.01); C07C 227/04 (2013.01); C07C 229/08 (2013.01); C07C 229/36 (2013.01); C07C 269/00 (2013.01); C07C 271/22 (2013.01); C07C 271/44 (2013.01); C07D 207/16 (2013.01); C07D 213/80 (2013.01); C07D 213/803 (2013.01); C07F 9/06 (2013.01); C07F 9/091 (2013.01); C07F 9/094 (2013.01); C07F 9/12 (2013.01); C07F 9/242 (2013.01); C07F 9/2458 (2013.01); C07F 9/65744 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01);
Abstract

The present invention relates to a phenol derivative and the preparation method and use in medicine thereof, and particular to a phenol derivative represented by general formula (A) or a stereoisomer, a solvate, a metabolite, a prodrug, a pharmaceutically acceptable salt or a cocrystal thereof, a preparation method thereof, a pharmaceutical composition comprising the same, and use of the compound or composition of the present invention in the field of the central nervous system; wherein the definitions of substituents in general formula (A) are the same as those in the Description.

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