The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Jun. 04, 2014
Applicant:
Cytomx Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Henry Bernard Lowman, El Granada, CA (US);
Luc Roland Desnoyers, San Francisco, CA (US);
Tony W. Liang, San Mateo, CA (US);
Andrei William Konradi, Burlingame, CA (US);
Shweta Singh, Fremont, CA (US);
Assignee:
CYTOMX THERAPEUTICS, INC., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 39/395 (2006.01); A61K 49/00 (2006.01); C07K 16/28 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48384 (2013.01); A61K 39/3955 (2013.01); A61K 47/48569 (2013.01); A61K 47/48715 (2013.01); A61K 49/00 (2013.01); C07K 16/18 (2013.01); C07K 16/2863 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01);
Abstract
The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.