The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2016

Filed:

May. 22, 2012
Applicants:

William G. Turnell, San Diego, CA (US);

Hong LI, San Diego, CA (US);

Zaza D. Gomurashvili, La Jolla, CA (US);

Ramaz Katsarava, Tbilisi, GE;

Inventors:

William G. Turnell, San Diego, CA (US);

Hong Li, San Diego, CA (US);

Zaza D. Gomurashvili, La Jolla, CA (US);

Ramaz Katsarava, Tbilisi, GE;

Assignee:

MEDIV AS, LLC, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/51 (2006.01); A61K 47/48 (2006.01); A61K 9/107 (2006.01); A61K 9/50 (2006.01); A61K 47/34 (2006.01); C07K 16/28 (2006.01); C08L 77/12 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 9/1647 (2013.01); A61K 9/5031 (2013.01); A61K 9/5153 (2013.01); A61K 47/34 (2013.01); A61K 47/482 (2013.01); A61K 47/48192 (2013.01); A61K 47/48207 (2013.01); C07K 16/2821 (2013.01); C08L 77/12 (2013.01); C12N 15/88 (2013.01); Y10S 977/773 (2013.01); Y10S 977/788 (2013.01); Y10S 977/906 (2013.01);
Abstract

The present invention provides biodegradable polymer particle delivery compositions based on polymers, such as polyester amide (PEA) and polyester urethane (PEUR) polymers, that contain amino acids in the polymer. The polymer particle delivery compositions can be formulated as a liquid dispersion of polymer particles with the bioactive agents dispersed in the particle or conjugated attached to polymer molecules or particle surfaces. The bioactive agents can include drugs, polypeptides, DNA and cells for cell-based therapies using particles sized for local, mucosal or circulatory delivery. Methods of treating a disease by administering to a subject the polymer particle delivery composition, which incorporates a bioactive agent suitable for treatment of the disease, or its symptoms, are also included.


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