The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2016

Filed:

Dec. 26, 2013
Applicants:

National University of Singapore, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Young-Tae Chang, Singapore, SG;

Jun Cheng Er, Singapore, SG;

Cheryl Kit Mun Leong, Singapore, SG;

Seong Wook Yun, Singapore, SG;

Marc Vendrell Escobar, Edinburgh, GB;

Mui Kee Tang, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); C09B 57/00 (2006.01); C09B 23/01 (2006.01); C09B 23/04 (2006.01); C07F 5/02 (2006.01); G01N 21/64 (2006.01); G01N 33/50 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/582 (2013.01); A61K 49/0021 (2013.01); C07F 5/022 (2013.01); C09B 23/0008 (2013.01); C09B 23/04 (2013.01); C09B 57/00 (2013.01); G01N 21/6428 (2013.01); G01N 33/5005 (2013.01); G01N 33/5058 (2013.01); G01N 2333/765 (2013.01); G01N 2458/30 (2013.01);
Abstract

A library of novel amino-triazolyl-BODIPY compounds is described. Particular compounds of the library serve as selective fluorescent probes for human serum albumin (HSA) and for live primary neurons. The fluorescent probe for HSA binds uniquely and specifically to the fatty acid site 1 of HSA, and thus proves a valuable and unique probe for drugs that bind to such a site on HSA. Methods of synthesis for the library compounds are also described.


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