The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9513286 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 06, 2016

Filed:

Jun. 28, 2006
Applicants:

Thomas P. Loughran, Jr., Hummelstown, PA (US);

Ravi Kothapalli, Wesley Chapel, FL (US);

Inventors:

Thomas P. Loughran, Jr., Hummelstown, PA (US);

Ravi Kothapalli, Wesley Chapel, FL (US);

Assignee:

UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); G01N 33/574 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57426 (2013.01); C12Q 1/6837 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/00 (2013.01);
Abstract

The subject invention concerns gene sequences and the use thereof as markers for large granular lymphocyte (LGL) leukemia. The gene sequences of the invention are differentially expressed in LGL. Another aspect of the invention pertains to therapeutic compositions directed to gene expression and gene products of differentially expressed genes in LGL. The invention also concerns methods for screening and identifying compositions that may be of therapeutic benefit to patients having LGL leukemia and/or autoimmune disorders. In addition, because a large fraction of patients with T-LGL leukemia also have rheumatoid arthritis, these differentially expressed genes also represent novel targets for the diagnosis, prevention or treatment of rheumatoid arthritis and other autoimmune diseases.


Find Patent Forward Citations

Loughran, Jr., Thomas. (2016). Differentially expressed genes in large granular lymphocyte leukemia (U.S. Patent No. 9513286). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9513286

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