The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2016
Filed:
Nov. 14, 2013
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Richard Haugland, Eugene, OR (US);
Wai-Yee Leung, San Ramon, CA (US);
Jixiang Liu, Sunnyvale, CA (US);
Assignee:
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/536 (2006.01); C07C 309/38 (2006.01); C07D 207/16 (2006.01); C07D 207/46 (2006.01); C07D 211/56 (2006.01); C07D 211/62 (2006.01); C07D 401/12 (2006.01); C07H 17/08 (2006.01); C07H 19/04 (2006.01); C07D 211/60 (2006.01); C07K 14/77 (2006.01); C07K 16/18 (2006.01); C09B 57/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/536 (2013.01); C07C 309/38 (2013.01); C07D 207/16 (2013.01); C07D 207/46 (2013.01); C07D 211/56 (2013.01); C07D 211/60 (2013.01); C07D 211/62 (2013.01); C07D 401/12 (2013.01); C07H 17/08 (2013.01); C07H 19/04 (2013.01); C07K 14/77 (2013.01); C07K 16/18 (2013.01); C09B 57/001 (2013.01);
Abstract
The invention provides a novel class of reactive fluorescent agents that are based on a pyrene sulfonic acid nucleus. The agents are readily incorporated into conjugates with other species by reacting the reactive group with a group of complementary reactivity on the other species of the conjugate. Also provided are methods of using the compounds of the invention to detect and/or quantify an analyte in a sample. In an exemplary embodiment, the invention provides multi-color assays incorporating the compounds of the invention.