The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2016

Filed:

Aug. 14, 2013
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Lin Pang, San Diego, CA (US);

Yeshaiahu Fainman, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01J 3/44 (2006.01); G01N 21/65 (2006.01); B22F 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/658 (2013.01); B22F 1/0044 (2013.01);
Abstract

Systems, devices and techniques are disclosed for optically detecting single molecules using nanoscale chip configurations. In one aspect, a sensing device includes a composite membrane having an array of nanochannels that form openings at opposing sides of the membrane, a first and second substrate each including channels to carry a fluid containing particles, a fluidic module that is fluidically coupled to the channels to supply the fluid, a plurality of electrodes located along the channels, and an electrical module to generate an electric field via the electrodes to effectuate an electrokinetic force within the channels to steer the particles toward the openings of the nanochannels to immobilize the particles, in which the nanochannels operate as resonant structures to amplify localized fields produced in an optical interrogation of the immobilized particles.


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