The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2016
Filed:
Feb. 06, 2014
Applicant:
Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh), Neuherberg, DE;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/0784 (2010.01); A61K 35/15 (2015.01); A61K 39/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0639 (2013.01); A61K 35/15 (2013.01); A61K 39/0011 (2013.01); C12N 15/85 (2013.01); C12N 2501/02 (2013.01); C12N 2501/23 (2013.01); C12N 2501/24 (2013.01); C12N 2501/25 (2013.01); C12N 2501/999 (2013.01);
Abstract
The invention relates to a method for in vitro maturation of at least one immate dendritic cell, comprising stimulating said immature dendritic cell with TNFα, IL-1β, IFNγ, a TLR7/8 agonist and prostaglandin E2(PG). Furthermore, the invention elates to a composition comprising these factors as well as to mature dendritic cells produced by a method of the invention.