The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2016

Filed:

Jun. 18, 2014
Applicants:

Kurt Alex Heldwein, Belmont, MA (US);

Igor Splawski, Winchester, MA (US);

Jennifer Brogdon, Sudbury, MA (US);

Joshua Goldstein, San Diego, CA (US);

William Dole, Ipswich, MA (US);

John Trauger, Cambridge, MA (US);

Chonghui Zhang, Brookline, MA (US);

Inventors:

Kurt Alex Heldwein, Belmont, MA (US);

Igor Splawski, Winchester, MA (US);

Jennifer Brogdon, Sudbury, MA (US);

Joshua Goldstein, San Diego, CA (US);

William Dole, Ipswich, MA (US);

John Trauger, Cambridge, MA (US);

Chonghui Zhang, Brookline, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 14/47 (2006.01); A61P 9/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 39/3955 (2013.01); C07K 16/2851 (2013.01); A61K 2039/505 (2013.01); C07K 14/4726 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates to monoclonal antibodies binding to human lectin-like oxidized LDL (low density lipoprotein) receptor 1 (hereinafter, sometimes referred to as 'LOX-1'), and pharmaceutical compositions and methods of treatment comprising the same.


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