The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2016

Filed:

May. 02, 2014
Applicant:

Her Majesty the Queen IN Right of Canada As Represented BY the Minister of Health, Winnipeg, CA;

Inventors:

Raymond Tsang, Winnipeg, CA;

Jody Berry, Winnipeg, CA;

Xin Yuan, Winnipeg, CA;

Cindi Corbett, Winnipeg, CA;

Mike Gubbins, Winnipeg, CA;

Amin Kabani, Winnipeg, CA;

Lisa Schmidt, Winnipeg, CA;

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 47/00 (2006.01); C07K 16/12 (2006.01); A61K 39/39 (2006.01); A61K 35/74 (2015.01); C07K 14/32 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1278 (2013.01); A61K 35/74 (2013.01); A61K 38/00 (2013.01); A61K 39/39 (2013.01); A61K 2039/505 (2013.01); C07K 14/32 (2013.01); C07K 16/1275 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The characterization and isolation of F20G75, F20G76 and F20G77, anti-PA monoclonal antibodies which also have neutralizing activities is described. The monoclonal antibodies may be used as a pharmaceutical composition for treating individuals suspected of or at risk of or having ainfection. The monoclonal antibodies bind to a specific region comprising amino acids 311-316 of PA, ASFFDI or a larger fragment comprising amino acids 301-330 of PA, SEVHGNAEVHASFFDIGSSVSAGFSNSNSS. Vaccines comprising these peptides may be used to immunize individuals againstinfection.


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