The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2016
Filed:
Aug. 01, 2011
Andreas Loew, Somerville, MA (US);
Brian Edward Vash, Cambridge, MA (US);
Shohei Koide, Chicago, IL (US);
John Bernard Wojcik, Chicago, IL (US);
Akiko Koide, Chicago, IL (US);
Ryan Nicholas Gilbreth, Chicago, IL (US);
Andreas Loew, Somerville, MA (US);
Brian Edward Vash, Cambridge, MA (US);
Shohei Koide, Chicago, IL (US);
John Bernard Wojcik, Chicago, IL (US);
Akiko Koide, Chicago, IL (US);
Ryan Nicholas Gilbreth, Chicago, IL (US);
NOVARTIS AG, Basel, CH;
UNIVERSITY OF CHICAGO, Chicago, IL (US);
Abstract
The here described invention discloses a combination of a top and bottom loop binder library using the CD and the FG loops of a number of FnIII domains (FnIII) (e.g., FnIII, FnIIIand FnIII) together with the surface exposed residues of the beta-sheet. The invention also pertains to a method of forming a library of FnIII domain polypeptides useful in screening for the presence of one or more polypeptides having a selected binding or enzymatic activity.