The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2016
Filed:
Jan. 23, 2015
Baxalta Incorporated, Bannockburn, IL (US);
Baxalta Gmbh, Glattpark (Opfikon), CH;
Katharina Nora Steinitz, Siegenfeld, AT;
Paula Maria Wilhelmina van Helden, DV Den Bosch, NL;
Birgit Maria Reipert, Deutsch-Wagram, AT;
Hans-Peter Schwarz, Vienna, AT;
Hartmut Ehrlich, Vienna, AT;
Baxalta Incorporated, Bannockburn, IL (US);
Baxalta GmbH, Glattpark (Opfikon), CH;
Abstract
The present invention is related to peptides that can be used to reduce the immune response against FVIII or to induce tolerance to human FVIII in patients with, e.g., hemophilia A. Furthermore, the peptides can be used for immunodiagnostic purposes to detect FVIII-specific CD4T cells to monitor patients with hemophilia A during replacement therapy and during immune tolerance induction therapy.