The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2016
Filed:
Oct. 31, 2014
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventors:
Assignee:
Case Western Reserve University, Cleveland, OH (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/04 (2006.01); C07C 319/12 (2006.01); C07C 323/25 (2006.01); C07D 207/46 (2006.01); C08G 2/00 (2006.01);
U.S. Cl.
CPC ...
C07C 323/25 (2013.01); A61K 49/0438 (2013.01); A61K 49/0442 (2013.01); C07C 319/12 (2013.01); C07D 207/46 (2013.01);
Abstract
Biodegradable computed tomography (CT) contrast agents comprising a polyiodinated aryl contrast agent that is crosslinked by an organic disulfide are described herein. The contrast agents can be used to image a tissue region by administering an effective amount of the biodegradable CT contrast agent to a subject, allowing a sufficient amount of time for the biodegradable CT contrast agent to enter the tissue region, and performing x-ray computed tomography imaging of the tissue region of the subject.