The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2016

Filed:

Mar. 14, 2014
Applicants:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Lehigh University, Bethlehem, PA (US);

Inventors:

Jeffrey D. Laskin, Piscataway, NJ (US);

Ned D. Heindel, Easton, PA (US);

Diane E. Heck, Rumson, NJ (US);

Carl Jeffrey Lacey, Schnecksville, PA (US);

Sherri C. Young, Clinton, NJ (US);

Assignees:

RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);

LEHIGH UNIVERSITY, Bethlehem, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 261/00 (2006.01); C07C 269/00 (2006.01); C07C 271/00 (2006.01); C07C 271/52 (2006.01); A61K 47/48 (2006.01); A61K 31/132 (2006.01); A61K 31/198 (2006.01); A61K 31/27 (2006.01); A61K 31/4015 (2006.01); A61K 31/405 (2006.01); C07C 271/16 (2006.01); C07C 271/22 (2006.01); C07C 271/48 (2006.01); C07D 207/16 (2006.01); C07D 209/26 (2006.01); C07C 271/12 (2006.01); C07C 271/34 (2006.01); C07C 271/50 (2006.01);
U.S. Cl.
CPC ...
C07C 271/52 (2013.01); A61K 31/132 (2013.01); A61K 31/198 (2013.01); A61K 31/27 (2013.01); A61K 31/405 (2013.01); A61K 31/4015 (2013.01); A61K 47/48038 (2013.01); C07C 271/12 (2013.01); C07C 271/16 (2013.01); C07C 271/22 (2013.01); C07C 271/34 (2013.01); C07C 271/48 (2013.01); C07C 271/50 (2013.01); C07D 207/16 (2013.01); C07D 209/26 (2013.01); C07C 2101/16 (2013.01); C07C 2102/42 (2013.01);
Abstract

Augmented or synergized anti-inflammatory constructs are disclosed including terpenes covalently conjugated with other anti-inflammatory molecules such as nonsteroidal anti-inflammatory drugs, vanilloids, amino acids and polyamines; and anti-inflammatory molecules covalently conjugated with specific amino acids. For the latter, further conjugation with a choline bioisostere further augments the anti-inflammatory activity.


Find Patent Forward Citations

Loading…