The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2016

Filed:

Sep. 13, 2011
Applicants:

Bryce C. Chackerian, Albuquerque, NM (US);

David S. Peabody, Albuquerque, NM (US);

Inventors:

Bryce C. Chackerian, Albuquerque, NM (US);

David S. Peabody, Albuquerque, NM (US);

Assignee:

STC.UNM, Albuquerque, NM (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/155 (2006.01); A61K 39/295 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 47/48 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/155 (2013.01); A61K 39/12 (2013.01); A61K 39/295 (2013.01); A61K 47/48776 (2013.01); A61K 47/48884 (2013.01); C07K 14/005 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/6075 (2013.01); C12N 2760/18534 (2013.01);
Abstract

The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of Respiratory Syncytial Virus (RSV) infections and related disorders, including bronchiolitis and viral pneumonia. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against RSV. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against RSV infection, confer immunity against RSV infection, protect against RSV infection, and reduce the likelihood of infection by RSV infection.


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