The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2016
Filed:
Oct. 18, 2012
Applicant:
Csl Behring Gmbh, Marburg, DE;
Inventors:
Sabine Zollner, Muri, CH;
Hubert Metzner, Marburg, DE;
Assignee:
CSL Behring GmbH, Marburg, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61K 38/37 (2006.01); A61K 47/36 (2006.01); A61K 38/47 (2006.01); A61K 47/26 (2006.01); A61K 31/727 (2006.01); A61K 31/728 (2006.01);
U.S. Cl.
CPC ...
A61K 38/37 (2013.01); A61K 31/727 (2013.01); A61K 31/728 (2013.01); A61K 38/47 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); C12Y 302/01025 (2013.01); C12Y 302/01035 (2013.01);
Abstract
The present invention relates to pharmaceutical preparations comprising Factor VIII, a sulfated glycosaminoglycan and a hyaluronidase for the non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders. The invention further relates to the combined use of a Factor VIII, a sulfated glycosaminoglycan and a hyaluronidase for the treatment and prevention of bleeding disorders, and to a method for increasing the bioavailability after non-intravenous administration of Factor VIII by co-administration of a sulfated glycosaminoglycan and a hyaluronidase.