The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Jan. 17, 2014
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Stephen A. Boppart, Champaign, IL (US);

Youbo Zhao, Urbana, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01J 3/44 (2006.01); G01N 21/47 (2006.01); G01N 21/64 (2006.01); G01N 21/65 (2006.01); G02F 1/39 (2006.01); G02F 1/35 (2006.01);
U.S. Cl.
CPC ...
G01N 21/47 (2013.01); G01N 21/6486 (2013.01); G01N 21/65 (2013.01); G02F 1/39 (2013.01); G02F 1/3534 (2013.01); G02F 2001/3528 (2013.01); G02F 2001/392 (2013.01);
Abstract

Methods and apparatus for obtaining an image of light scattering biological tissue. A series of pulses of substantially monochromatic light of a first wavelength is generated and split into two parts, of which one part illuminates a scattering biological tissue at an intensity too low to damage the tissue, while a second part is upconverted to generate a pump beam. Sample light from the biological tissue, which may be scattered (or transmitted) light, or fluorescence, or Raman scattering, etc., is collected and directed from the scattering biological tissue, along with the pump beam, into a non-linear optical element, in a single pass or multiple passes. Parametrically amplified sample light emerging from the non-linear optical element is detected and analyzed or displayed.


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