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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9506070 B1

PDFFull Text
Expired
Date of Patent:
Nov. 29, 2016

Filed:

Nov. 21, 2013

Aptamer against midkine and applications thereof

Applicants:

Ribomic Inc., Tokyo, JP;

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Shin Miyakawa, Tokyo, JP;

Masatoshi Fujiwara, Tokyo, JP;

Yoshikazu Nakamura, Tokyo, JP;

Kenji Kadomatsu, Aichi, JP;

Ping Mu, Aichi, JP;

Assignees:

RIBOMIC INC., Tokyo, JP;

OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;

Attorney:

Wenderoth, Lind & Ponack, L.L.P.

Primary Examiner:

Amy Bowman

Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/115 (2010.01); A61K 47/48 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 31/7088 (2013.01); A61K 31/711 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 47/48092 (2013.01); C12N 2310/16 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/335 (2013.01); C12N 2310/351 (2013.01); C12N 2310/531 (2013.01); C12N 2320/30 (2013.01);
Abstract

The present invention provides an aptamer binding to midkine and capable of forming a potential secondary structure represented by the formula (I): whereinX1, X2, X5 and X6 are the same or different and each is one or two nucleotides selected from the group consisting of A, G, C, U and T, or a bond,X1 and X6, and X2 and X5 each form a Watson-Crick base pairs, andX3 and X4 are the same or different and each is a nucleotide selected from A, G, C, U and T.

Find Patent Forward Citations

Miyakawa, Shin. (2016). Aptamer against midkine and applications thereof (U.S. Patent No. 9506070). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9506070

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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