The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Feb. 15, 2013
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Belrose Pharma Inc., Princeton, NJ (US);
Rajanikanth Bandaru, Warren, NJ (US);
Yixian Zhang, Piscataway, NJ (US);
Zhengxing Qu, Warren, NJ (US);
Lee Greenberger, Montclair, NJ (US);
Christopher Ott, Boston, MA (US);
James Elliott Bradner, Boston, MA (US);
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
ENZON PHARMACEUTICALS, INC., Cranford, NJ (US);
Abstract
The disclosure relates to oligonucleotide compounds (oligomers) that target Myc mRNA in a cell, leading to reduced expression of Myc. Reduction of Myc expression is beneficial for the treatment of certain disorders, such as hyperproliferative disorders (e.g., cancer). The disclosure provides therapeutic compositions comprising oligomers and methods for modulating the expression of Myc using said oligomers, including methods of treatment.