The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

May. 21, 2010
Applicants:

Victor Maltsev, Parkville, MD (US);

Edward G. Lakatta, Bel Air, MD (US);

Ihor Zahanich, Towson, MD (US);

Syevda Sirenko, Dortmund, DE;

Maxim Mikheev, Pittsburgh, PA (US);

Yoram Vodovotz, Sewickley, PA (US);

Inventors:

Victor Maltsev, Parkville, MD (US);

Edward G. Lakatta, Bel Air, MD (US);

Ihor Zahanich, Towson, MD (US);

Syevda Sirenko, Dortmund, DE;

Maxim Mikheev, Pittsburgh, PA (US);

Yoram Vodovotz, Sewickley, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 48/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); A61K 48/005 (2013.01); C12N 15/86 (2013.01); C12N 2500/14 (2013.01); C12N 2501/01 (2013.01); C12N 2506/02 (2013.01); C12N 2510/00 (2013.01); C12N 2740/15043 (2013.01); C12N 2830/002 (2013.01);
Abstract

Biological pacemakers engineered to intrinsically generate rhythmic excitations are disclosed. In addition, methods of producing the biological pacemakers are disclosed. Methods of treating or preventing arrhythmia and heart disease associated with a defective pacemakers are also disclosed.


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