The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Mar. 17, 2014
Applicants:

Amgen Research (Munich) Gmbh, Munich, DE;

Vib Vzw, Ghent, BE;

Universiteit Gent, Ghent, BE;

Inventors:

Peter Kufer, Munich, DE;

Tobias Raum, Munich, DE;

Markus Muenz, Munich, DE;

Jochen Pendzialek, Munich, DE;

Walter Fiers, Destelbergen, BE;

Xavier Saelens, Ypres, BE;

Kenny Roose, Ettelgem, BE;

Assignees:

AMGEN RESEARCH (MUNICH) GMBH, Munich, DE;

VIB VZW, Ghent, BE;

Universiteit Gent, Ghent, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2006.01); A61K 45/06 (2006.01); C07K 16/46 (2006.01); C07K 16/10 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); C07K 16/1018 (2013.01); C07K 16/2809 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates to an antibody construct comprising a first human binding domain specific for the extracellular part of the influenza envelope protein M2 (M2e) and a second domain specific for CD3. Moreover, the invention provides a nucleic acid molecule encoding the antibody construct, a vector comprising said nucleic acid molecule and a host cell transformed or transfected with said nucleic acid molecule or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a pharmaceutical composition comprising said antibody construct, a medical use/method of treatment relating to said antibody construct, and a kit comprising said antibody construct.


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