The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Apr. 18, 2014
Applicants:

Wyeth Llc, Madison, NY (US);

William J. Dunham, Belgrade, ME (US);

Inventors:

Jane Aghajanian, Belgrade, ME (US);

Neil M. Wolfman, Dover, MA (US);

Denise O'Hara, Reading, MA (US);

Monique V. Davies, Harpswell, MA (US);

Geertruida M. Veldman, Sudbury, MA (US);

Kristie Grove Bridges, Maynard, MA (US);

Lisa-Anne Whittemore, East Walpole, MA (US);

Tejvir S. Khurana, Narberth, PA (US);

Mary L. Bouxsein, Brookline, MA (US);

Assignee:

Wyeth LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 5/00 (2006.01); C07K 16/22 (2006.01); C07K 14/475 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); C07K 14/475 (2013.01); A01K 2217/075 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01);
Abstract

The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle, bone, or insulin metabolism.


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