The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Aug. 19, 2011
Applicants:

Susan E. Lacy, Westborough, MA (US);

Jeffrey A. Barbon, Groton, MA (US);

Meha Chhaya, Shrewsbury, MA (US);

Emma Fung, Northborough, MA (US);

Charles W. Hutchins, Green Oaks, IL (US);

Diane M. Lang, Hope Valley, RI (US);

Eve H. Barlow, Wellesley, MA (US);

Mary Leddy, North Atteboro, MA (US);

Ravi Chari, Norwich, CT (US);

Inventors:

Susan E. Lacy, Westborough, MA (US);

Jeffrey A. Barbon, Groton, MA (US);

Meha Chhaya, Shrewsbury, MA (US);

Emma Fung, Northborough, MA (US);

Charles W. Hutchins, Green Oaks, IL (US);

Diane M. Lang, Hope Valley, RI (US);

Eve H. Barlow, Wellesley, MA (US);

Mary Leddy, North Atteboro, MA (US);

Ravi Chari, Norwich, CT (US);

Assignee:

ZOETIS BELGIUM S.A., Louvain-la-Neuve, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/50 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/60 (2013.01); C07K 2317/622 (2013.01); C07K 2317/624 (2013.01); C07K 2317/626 (2013.01); C07K 2317/64 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present disclosure encompasses NGF binding proteins, specifically to antibodies that are chimeric, CDR grafted and canonized antibodies, and methods of making and uses thereof. The antibodies, or antibody portions, of the disclosure are useful for detecting NGF and for inhibiting NGF activity, e.g., in a mammal subject suffering from a disorder in which NGF activity is detrimental.


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