The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Dec. 22, 2011
Applicants:
David Wilson, Fremont, CA (US);
Tetsuya Taura, Palo Alto, CA (US);
Inventors:
David Wilson, Fremont, CA (US);
Tetsuya Taura, Palo Alto, CA (US);
Assignee:
Teva Pharmaceuticals Australia Pty Ltd, Macquarie Park, NSW, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); A61K 39/40 (2006.01); C07K 16/28 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 16/2803 (2013.01); C07K 2317/52 (2013.01); C07K 2317/90 (2013.01);
Abstract
The present invention relates to antibodies, immunoglobulin constructs or immunoglobulin IgG4 fusion proteins whose in vivo half-lives are increased by the combination of (i) a modified IgG4 Fc region or FcRn binding domain thereof and (ii) a modified IgG4 hinge region sequence.