The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Apr. 20, 2016
Applicants:

The United States of America Represented BY the Department of Veterans Affairs, Washington, DC (US);

The Regents of the University of California, Oakland, CA (US);

Cornell Research Foundation, Inc., Ithaca, NY (US);

Fundação Oswaldo Cruz, Rio de Janeiro, BR;

Inventors:

Albert I. Ko, Salvador, BR;

Mitermayer Galvão Reis, Salvador, BR;

Julio Henrique Rosa Croda, Salvador, BR;

Isadora Cristina Siqueira, Salvador, BR;

David A. Haake, Los Angeles, CA (US);

James Matsunaga, Los Angeles, CA (US);

Lee W. Riley, Berkeley, CA (US);

Michele Barocchi, Los Angeles, CA (US);

Tracy Ann Young, Berkeley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07K 14/20 (2006.01);
U.S. Cl.
CPC ...
C07K 14/20 (2013.01);
Abstract

The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in thesp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection withspecies that are capable of producing disease in humans and other mammals, including those of veterinary importance.


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