The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Nov. 02, 2007
Applicants:

Theodore J. Nitz, Boyds, MD (US);

Christian Montalbetti, Wallingford, GB;

Richard Mears, Oxford, GB;

Xinjie Gai, Wallingford, GB;

Edward Glenn, Wantage, GB;

Inventors:

Theodore J. Nitz, Boyds, MD (US);

Christian Montalbetti, Wallingford, GB;

Richard Mears, Oxford, GB;

Xinjie Gai, Wallingford, GB;

Edward Glenn, Wantage, GB;

Assignee:

Myrexis, Inc., Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); C07J 53/00 (2006.01);
U.S. Cl.
CPC ...
C07J 53/00 (2013.01);
Abstract

The present invention concerns novel pharmaceutically active triterpene derivatives, pharmaceutical compositions containing the same, their use as medicaments, and the use of the compounds for the manufacture of specific medicaments. The present invention also concerns a method of treatment involving administration of the compounds. Specifically, the compounds are derivatives of betulinic acid having substitutions at one or more of the C-3, C2-8 and C-19 positions as further described herein. The novel compounds are useful as antiretroviral agents. In particular, the novel compounds are useful for the treatment of Human Immunodeficiency Virus (HIV).


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