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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9505799 B1

PDFFull Text
Date of Patent:
Nov. 29, 2016

Filed:

May. 11, 2012

18f-labeled precursor of pet radioactive medical supplies, and preparation method thereof

Applicants:

Dae-yoon Chi, Seoul, KR;

Byoung-se Lee, Incheon, KR;

Chansoo Park, Seoul, KR;

Min-hyung Lee, Goyang-si, KR;

Hyojin Cha, Bucheon-si, KR;

Woojin Cho, Seoul, KR;

Heewon Kang, Seongnam-si, KR;

Kyunghun Kim, Seoul, KR;

Inventors:

Dae-Yoon Chi, Seoul, KR;

Byoung-Se Lee, Incheon, KR;

Chansoo Park, Seoul, KR;

Min-Hyung Lee, Goyang-si, KR;

Hyojin Cha, Bucheon-si, KR;

Woojin Cho, Seoul, KR;

Heewon Kang, Seongnam-si, KR;

Kyunghun Kim, Seoul, KR;

Assignee:

Futurechem Co., Ltd., Seoul, KR;

Attorney:

Greer, Burns & Crain, Ltd.

Primary Examiner:

Alicia L Otton

Int. Cl.
CPC ...
C07D 249/04 (2006.01); C07D 249/06 (2006.01); C07J 43/00 (2006.01); A61K 51/04 (2006.01); C07D 233/60 (2006.01); C07B 59/00 (2006.01); C07C 43/225 (2006.01); C07C 229/36 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); A61K 51/04 (2013.01); A61K 51/0406 (2013.01); A61K 51/0493 (2013.01); C07B 59/00 (2013.01); C07B 59/007 (2013.01); C07C 43/225 (2013.01); C07C 229/36 (2013.01); C07D 233/60 (2013.01); C07D 249/04 (2013.01); C07D 249/06 (2013.01);
Abstract

The present invention relates to a precursor of positron emission tomography (PET) radioactive medical supplies, a preparation method thereof, and an application thereof, and more specifically, to a precursor having a tetravalent organic salt leaving group, a preparation method, and a method for preparing desired PET radioactive medical supplies in a high radiochemical yield within a short preparation time by introducingF using the same through a single step. The precursor having a tetravalent organic salt leaving group of the present invention can simplify the known complex multistep preparation of radioactive medical supplies into a single step, can save production costs because an excessive amount of a phase transfer catalyst is not required, facilitates separation of a compound after reaction, and enables rapid reaction velocity. The features are appropriate for the mass production of PET radioactive medical supplies by an automated synthesis system.

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