The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Nov. 28, 2011
Applicants:

Dan R. Littman, New York, NY (US);

Jun R. Huh, Newton, MA (US);

Nicolas Gabriel Albert Manel, Paris, FR;

Daniel A. Ryan, San Diego, CA (US);

David Y. Gin, Pelham, NY (US);

Mary S. Gin, Pelham, NY (US);

Michael R. Krout, Mifflinburg, PA (US);

Inventors:

Dan R. Littman, New York, NY (US);

Jun R. Huh, Newton, MA (US);

Nicolas Gabriel Albert Manel, Paris, FR;

Daniel A. Ryan, San Diego, CA (US);

David Y. Gin, Pelham, NY (US);

Michael R. Krout, Mifflinburg, PA (US);

Assignees:

New York University, New York, NY (US);

Memorial Sloan-Kettering Cancer Center, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 17/00 (2006.01); A61K 31/704 (2006.01); C07J 19/00 (2006.01);
U.S. Cl.
CPC ...
C07J 17/005 (2013.01); A61K 31/704 (2013.01); C07J 19/005 (2013.01);
Abstract

Steroid compounds are disclosed that have a formula represented by the following: and wherein m, n, t, u1, u2, v1, v2, R, R, R, R, R, R, R, R, and Y are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the treatment or prevention of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.


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