The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Feb. 22, 2013
Applicant:
Ewha University—industry Collaboration Foundation, Seoul, KR;
Inventors:
Assignee:
Intron Biotechnology, Inc., Seongnam-Si, Gyeonggi-Do, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/12 (2006.01); C12N 9/10 (2006.01); A61K 31/00 (2006.01); C07D 493/16 (2006.01); C12P 17/18 (2006.01); C07D 498/18 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C07D 493/16 (2013.01); C07D 498/18 (2013.01); C12N 9/1029 (2013.01); C12N 15/52 (2013.01); C12P 17/188 (2013.01); Y02P 20/52 (2015.11);
Abstract
The present invention relates to novel tacrolimus analogs, a composition for the prevention or treatment of neurological diseases or immune hypersensitivity disorders comprising the same, a method for preventing or treating neurological diseases or immune hypersensitivity disorders comprising administering the analogs to a subject, a method for preparing the analogs using an isolated modifiedsp. strain wherein the activity of one or more enzymes selected from the group consisting of TcsA, TcsB, TcsC and TcsD is reduced; and the isolated modifiedsp. strain for prepare the analogs.