The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Apr. 25, 2014
Applicant:

Glaxosmithkline Intellectual Property (No.2) Limited, Brentford, Middlesex, GB;

Inventors:

Charles William Blackledge, Jr., Collegeville, PA (US);

Joelle Lorraine Burgess, Collegeville, PA (US);

Neil W. Johnson, Collegeville, PA (US);

Jiri Kasparec, Collegeville, PA (US);

Steven David Knight, Collegeville, PA (US);

Louis V. LaFrance, III, Collegeville, PA (US);

Juan I. Luengo, Collegeville, PA (US);

William Henry Miller, Collegeville, PA (US);

Kenneth Allen Newlander, Collegeville, PA (US);

Stuart Paul Romeril, Collegeville, PA (US);

Mark Schulz, Collegeville, PA (US);

Dai-Shi Su, Collegeville, PA (US);

Xinrong Tian, Collegeville, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 409/14 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/14 (2013.01);
Abstract

This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.


Find Patent Forward Citations

Loading…