The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Nov. 27, 2012
Applicant:
Aquilus Pharmaceuticals, Inc., Winchester, MA (US);
Inventor:
Irving Sucholeiki, Winchester, MA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 403/12 (2006.01); A61K 45/06 (2006.01); C07D 239/28 (2006.01); C07D 413/12 (2006.01); A61K 31/505 (2006.01); A61K 31/538 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/538 (2013.01); A61K 45/06 (2013.01); C07D 239/28 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01);
Abstract
The present invention relates generally to bis-amide containing MMP inhibiting compounds, and more particularly to selectively deuterated bis-amide MMP-13 inhibiting compounds that exhibit increased stability or potency in relation to currently known MMP-13 inhibitors. Additionally, the present invention relates to methods for treating pain and inflammation in a patient comprising administering to the patient a pain-reducing effective amount of a present compound.