The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Oct. 08, 2014
Applicant:

Topokine Therapeutics, Inc., Newton, MA (US);

Inventor:

Murat V. Kalayoglu, Silver Spring, MD (US);

Assignee:

Topokine Therapeutics, Inc., Newton, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5575 (2006.01); C07C 405/00 (2006.01); A61P 3/04 (2006.01); A61K 31/5585 (2006.01); C07C 69/732 (2006.01); C07C 235/30 (2006.01); C07D 307/20 (2006.01); A61K 31/133 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5575 (2013.01); A61K 31/133 (2013.01); A61K 31/5585 (2013.01); C07C 69/732 (2013.01); C07C 235/30 (2013.01); C07D 307/20 (2013.01);
Abstract

Provided are methods, compositions, systems, and kits for treating metabolic syndrome or a disorder associated with metabolic syndrome, e.g., obesity, dyslipidemia, and/or a diabetic condition, comprising administering systemically to a subject one or more compounds of the Formula (I) and/or (II): or a pharmaceutically acceptable salt, hydrate, solvate, stereoisomer, polymorph, tautomer, isotopically enriched derivative, or prodrug thereof, wherein, L, R, R, Z, X, A and B are defined herein.


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