The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Mar. 16, 2012
Applicants:

Craig A. Coburn, Royersford, PA (US);

Stuart B. Rosenblum, West Orange, PA (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Richard Soll, San Diego, CA (US);

Hao Wu, Shanghai, CN;

Bin HU, Shanghai, CN;

Bin Zhong, Shanghai, CN;

Dahai Wang, Shanghai, CN;

Changmao Shen, Shanghai, CN;

Fei Sun, Shanghai, CN;

Inventors:

Craig A. Coburn, Royersford, PA (US);

Stuart B. Rosenblum, West Orange, PA (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Richard Soll, San Diego, CA (US);

Hao Wu, Shanghai, CN;

Bin Hu, Shanghai, CN;

Bin Zhong, Shanghai, CN;

Dahai Wang, Shanghai, CN;

Changmao Shen, Shanghai, CN;

Fei Sun, Shanghai, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/5383 (2006.01); C07D 491/06 (2006.01); C07D 498/06 (2006.01); A61K 31/4178 (2006.01); A61K 45/06 (2006.01); C07D 493/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5383 (2013.01); A61K 31/4178 (2013.01); A61K 45/06 (2013.01); C07D 491/06 (2013.01); C07D 493/06 (2013.01); C07D 498/06 (2013.01);
Abstract

The present invention relates to novel Tetracyclic Xanthene Derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, Y, Y, Z, R, R, R, Rand Rare as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Xanthene Derivative, and methods of using the Tetracyclic Xanthene Derivatives for treating or preventing HCV infection in a patient.


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