The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Jun. 16, 2014
Applicant:

Lupin Limited, Mumbai, IN (US);

Inventors:
Assignee:

Lupin Limited, Mumbai, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 207/333 (2006.01); C07D 401/04 (2006.01); A61K 31/40 (2006.01); A61K 45/06 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/40 (2013.01); A61K 45/06 (2013.01); C07D 207/333 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01);
Abstract

Disclosed are compounds of the formula (I), wherein R, R, R, R, R, R, Rand m are as described herein, as modulators of the nicotinic acetylcholine receptors, particularly the α7 subtype, their tautomeric forms, stereoisomers, and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and combinations thereof with suitable other medicaments. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and/or treatment of disorders such as Alzheimer's disease, mild cognitive impairment, and senile dementia.


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