The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Jul. 06, 2012
Applicants:
Diana Julie Leeming, Espergaerde, DK;
Morten Karsdal, Copenhagen, DK;
Efstathios Vassiliadis, Rodovre, DK;
Inventors:
Diana Julie Leeming, Espergaerde, DK;
Morten Karsdal, Copenhagen, DK;
Efstathios Vassiliadis, Rodovre, DK;
Assignee:
Nordic Bioscience A/S, Herlev, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); C07K 16/18 (2006.01); C07K 14/47 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6887 (2013.01); C07K 14/4716 (2013.01); C07K 16/18 (2013.01); G01N 33/566 (2013.01); G01N 33/6893 (2013.01); C07K 2317/34 (2013.01); G01N 2333/4712 (2013.01); G01N 2800/32 (2013.01);
Abstract
An immunoassay for the quantification of fragments having an N- or a C-terminal neo-epitope formed by cleavage of a titin protein by a proteinase is provided. The immunoassay includes the steps of contacting a sample with an antibody specifically binding to the N- or C-terminal neo-epitope of the fragments and determining the level of binding.