The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Jun. 06, 2014
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Weiguo Andy Tao, West Lafayette, IN (US);
Changdeng Hu, West Lafayette, IN (US);
Lingfel Zeng, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12Q 1/68 (2006.01); G01N 33/573 (2006.01); C12Q 1/48 (2006.01); C12Q 1/66 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C12Q 1/485 (2013.01); G01N 33/6845 (2013.01); G01N 33/6848 (2013.01); G01N 2333/912 (2013.01);
Abstract
The invention generally relates to methods for identifying protein-protein interactions. In certain aspects, methods of the invention involve conducting a protein-fragment complementation assay on a sample to form a protein-protein complex between two proteins in the sample that only transiently interact under physiological conditions, separating the complexes from the sample, and analyzing a protein of the complex using a mass spectrometry technique.