The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Oct. 31, 2012
National Institute of Advanced Industrial Science and Technology, Tokyo, JP;
Wako Pure Chemical Industries, Ltd., Osaka, JP;
Hiroaki Tateno, Ibaraki, JP;
Jun Hirabayashi, Ibaraki, JP;
Yuzuru Ito, Ibaraki, JP;
Yasuko Onuma, Ibaraki, JP;
Makoto Asashima, Ibaraki, JP;
Atsushi Kuno, Ibaraki, JP;
Masaki Warashina, Hyogo, JP;
Masakazu Fukuda, Hyogo, JP;
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, Tokyo, JP;
WAKO PURE CHEMICAL INDUSTRIES, LTD., Osaka, JP;
Abstract
An object of the present invention is to provide a method for evaluating a differentiation status of cells using a culture supernatant of stem cells. Provided is 'undifferentiation sugar chain marker' composed of the sugar chain structure 'Fucα1-2Galβ1-3GlcNAc' or “Fucα1-2Galβ1-3GalNAc” and capable of sensitively determining the undifferentiated state of stem cells using a culture supernatant of stem cells. Also found is BC2LCN lectin or a modified product thereof capable of sensitively recognizing the “undifferentiation sugar chain marker” as excellent “probe for detecting the undifferentiation sugar chain marker” capable of determining the undifferentiation status of cells using a culture supernatant.