The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Dec. 14, 2012
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Arthur Prindle, San Diego, CA (US);

Phillip Samayoa, La Jolla, CA (US);

Jeff Hasty, Encinitas, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/18 (2006.01); C12Q 1/02 (2006.01); C12N 15/70 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/1866 (2013.01); C12N 15/70 (2013.01); C12Q 1/02 (2013.01); C12Q 1/6897 (2013.01);
Abstract

This invention provides a multiscale platform for coordinating behavior using synthetic biology. The platform reduces the impact of underlying noise, making outputs more coherent and reliable at the macroscopic level. In one aspect, the invention provides a frequency-modulated biosensor, comprising a microfluidic array comprising two or more separate colonies or populations of sensing cells to grow and communicate by gas exchange, wherein the colonies or populations of sensing cells output synchronized oscillating signals.


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