The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Oct. 15, 2013
Applicants:

Institut Pasteur, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Frederic Tangy, Les Lilas, FR;

Pierre Charneau, Paris, FR;

Yves Jacob, Maintenon, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C12N 2740/16021 (2013.01); C12N 2740/16043 (2013.01); C12N 2740/16052 (2013.01); C12N 2760/18022 (2013.01); C12N 2760/18422 (2013.01); C12N 2830/48 (2013.01);
Abstract

The present invention relates to recombinant cells as well as to methods for the generation of non-segmented negative-sense single-stranded RNA viruses (NNV or mononegavirales) from cloned deoxyribonucleic acid (cDNA), especially from measles virus and in particular from attenuated strains such as those approved for vaccination, in particular from the attenuated Schwarz measles virus and various recombinant Schwarz measles-based viruses expressing heterologous sequences. Such rescued viruses can be used, after amplification, as vaccines for immunization against measles and/or against the heterologous peptides or proteins expressed.


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