The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Oct. 03, 2008
Applicants:

Thomas Payne, Pittsburgh, PA (US);

Ronald Jankowski, Pittsburgh, PA (US);

Ryan Pruchnic, Pittsburgh, PA (US);

Michael Chancellor, Pittsburgh, PA (US);

Inventors:

Thomas Payne, Pittsburgh, PA (US);

Ronald Jankowski, Pittsburgh, PA (US);

Ryan Pruchnic, Pittsburgh, PA (US);

Michael Chancellor, Pittsburgh, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/34 (2006.01); C12N 5/077 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0659 (2013.01); A61K 35/34 (2013.01); C12N 5/0658 (2013.01); A61K 35/12 (2013.01); C12N 2500/84 (2013.01); C12N 2501/70 (2013.01); C12N 2510/00 (2013.01); C12N 2533/54 (2013.01);
Abstract

The present invention provides muscle-derived progenitor cells (MDCs) that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction into a site of soft tissue. Also provided are methods of isolating MDCs. The invention further provides methods of using compositions comprising MDCs for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. The invention also relates to uses of MDCs for the treatment of cosmetic or functional conditions, including, but not limited to skeletal muscle weakness, muscular dystrophy, muscle atrophy, spasticity, myoclonus and myalgia. The invention also relates to the use of MDCs for the increase of skeletal muscle.


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