The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Feb. 05, 2013
Applicant:

Dongguk University Industry-academic Cooperation Foundation, Seoul, KR;

Inventors:

Jung Keug Park, Seoul, KR;

Hee Hoon Yoon, Gyeonggi-do, KR;

Soo Yeon Kim, Gyeonggi-do, KR;

Young Kwon Seo, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0618 (2013.01); C12N 2500/44 (2013.01); C12N 2501/33 (2013.01); C12N 2501/39 (2013.01); C12N 2501/999 (2013.01); C12N 2506/1346 (2013.01); C12N 2506/1384 (2013.01);
Abstract

The present invention relates to a method for differentiating stem cells into neurons, and is characterized in that stem cells are treated with a culture additive comprising lipoic acid, albumin, hydrocortisone, and insulin after culturing for differentiation into neurons. Since the neurons produced according to the method for producing neurons of the present invention express nestin, neuroD1, neuron-specific enolase (NSE), neurofilament (NF), tau, microtubule-associated protein 2 (MAP2), and doublecortin (DCX), just as normal mature neurons do, the neurons of the present invention can be effectively used in various therapeutic agents for neurons and as cell origins for an in vitro study system.


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