The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Jul. 20, 2015
Applicant:

Abbvie Biotechnology Ltd, Hamilton, BM;

Inventors:

Rebecca S. Hoffman, Wilmette, IL (US);

Elliot K. Chartash, Randolph, NJ (US);

Lori K. Taylor, Wadsworth, IL (US);

George R. Granneman, Lindenhurst, IL (US);

Philip Yan, Vernon Hills, IL (US);

Assignee:

ABBVIE BIOTECHNOLOGY LTD, Hamilton, BM;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/24 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); A61K 9/0019 (2013.01); A61K 39/3955 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract

Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.


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