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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9499606 B1

PDFFull Text
Date of Patent:
Nov. 22, 2016

Filed:

Aug. 02, 2013

Compositions of, and methods for, alpha-1 anti trypsin fc fusion molecules

Applicant:

The Regents of the University of Colorado, a Body Corporate, Boulder, CO (US);

Inventor:

Leland Shapiro, Denver, CO (US);

Assignee:

The Regents of the University of Colorado, a body corporate, Boulder, CO (US);

Attorney:

Faegre Baker Daniels LLP

Primary Examiner:

Gary Nickol

Assistant Examiner:

Lakia Tongue

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 45/00 (2006.01); A61K 47/00 (2006.01); A61K 39/42 (2006.01); A61K 39/395 (2006.01); A61K 39/38 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); C07K 14/81 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61K 38/57 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/8125 (2013.01); A61K 31/519 (2013.01); A61K 38/57 (2013.01); A61K 45/06 (2013.01); C07K 14/473 (2013.01); C07K 14/811 (2013.01); C07K 16/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/23 (2013.01); C07K 2319/30 (2013.01); C07K 2319/43 (2013.01); C07K 2319/50 (2013.01);
Abstract

A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB),complex (MAC), and anthrax in particular. Thus, the invention relates to modulation of cellular activities, including macrophage activity, and the like. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease.

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