The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Sep. 14, 2012
Applicants:

Haiyong Wang, Beijing, CN;

Jing LI, Beijing, CN;

Inventors:

Haiyong Wang, Beijing, CN;

Jing Li, Beijing, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/43 (2006.01); A61K 31/496 (2006.01); C07D 499/887 (2006.01); C07D 499/00 (2006.01); C07D 499/04 (2006.01); C07D 499/68 (2006.01);
U.S. Cl.
CPC ...
C07D 499/887 (2013.01); A61K 31/43 (2013.01); A61K 31/496 (2013.01); C07D 499/00 (2013.01); C07D 499/04 (2013.01); C07D 499/68 (2013.01);
Abstract

Provided in the present invention are a cocrystal of piperacillin sodium and sulbactam sodium and preparation method thereof, as well as pharmaceutical compositions containing the same and uses thereof in treating infections caused by drug-resistant bacteria, such as a 'super bacterium' producing NDM-1 and the like. The cocrystal of piperacillin sodium and sulbactam sodium contains diffraction angles of 14.24°, 16.58°, 16.79°, 17.77°, 19.20°, 20.21°, 20.39°, 23.06°, 27.86° and 32.16° represented by 2θ in an X-ray powder diffraction analysis spectrum.


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