IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9499553 B1

PDFFull Text
Date of Patent:
Nov. 22, 2016

Filed:

Sep. 14, 2015

Dihydropyridazine-3,5-dione derivative and pharmaceuticals containing the same

Applicant:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Yoshihito Ohtake, Shizuoka, JP;

Naoki Okamoto, Shizuoka, JP;

Yoshiyuki Ono, Shizuoka, JP;

Hirotaka Kashiwagi, Shizuoka, JP;

Atsushi Kimbara, Shizuoka, JP;

Takeo Harada, Shizuoka, JP;

Nobuyuki Hori, Shizuoka, JP;

Yoshihisa Murata, Shizuoka, JP;

Kazutaka Tachibana, Shizuoka, JP;

Shota Tanaka, Shizuoka, JP;

Kenichi Nomura, Shizuoka, JP;

Mitsuaki Ide, Shizuoka, JP;

Eisaku Mizuguchi, Shizuoka, JP;

Yasuhiro Ichida, Shizuoka, JP;

Shuichi Ohtomo, Shizuoka, JP;

Naoshi Horiba, Shizuoka, JP;

Assignee:

CHUGAI SEIYAKU KABUSHIKI KAISHA, Tokyo, JP;

Attorney:

Browdy and Neimark, P.L.L.C.

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Lance Rider

Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/5025 (2006.01); C07D 403/12 (2006.01); C07D 471/04 (2006.01); C07D 491/107 (2006.01); A61K 31/504 (2006.01); A61K 31/5377 (2006.01); A61K 31/506 (2006.01); C07D 401/12 (2006.01); A61K 31/503 (2006.01); C07D 401/14 (2006.01); C07D 491/08 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/503 (2013.01); A61K 31/504 (2013.01); A61K 31/506 (2013.01); A61K 31/5025 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01); C07D 491/08 (2013.01); C07D 491/107 (2013.01);
Abstract

The present invention provides a dihydropyridazine-3,5-dione derivative or a salt thereof, or a solvate of the compound or the salt, a pharmaceutical drug, a pharmaceutical composition, a sodium-dependent phosphate transporter inhibitor, and a preventive and/or therapeutic agent for hyperphosphatemia, secondary hyperparathyroidism, chronic renal failure, chronic kidney disease, and arteriosclerosis associated with vascular calcification comprising the compound as an active ingredient, and a method for prevention and/or treatment.

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