The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Apr. 22, 2014
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Kenneth L. Arrington, Lansdale, PA (US);

Byron DuBois, New York, NY (US);

John S. Debenham, Scotch Plains, NJ (US);

Ping Liu, Westfield, NJ (US);

Alan B. Northrup, Reading, MA (US);

Jason W. Szewczyk, Pennsburg, PA (US);

Liping Wang, Dayton, NJ (US);

Ming Wang, Belle Mead, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); A61K 31/427 (2006.01); C07D 417/12 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/427 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); C07D 417/12 (2013.01);
Abstract

The invention provides certain thiazole-substituted aminopyrimidine compounds of the Formula (I) (I), or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R5, R6, and the subscripts r, s, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).


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