The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Dec. 26, 2013
Applicant:

Medivation Technologies, Inc., San Francisco, CA (US);

Inventors:

Sarvajit Chakravarty, Mountain View, CA (US);

Roopa Rai, San Carlos, CA (US);

Michael John Green, Half Moon Bay, CA (US);

Amantullah Ansari, Noida, IN;

Assignee:

MEDIVATION TECHNOLOGIES, INC., San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/84 (2006.01); C07D 401/14 (2006.01); C07D 491/107 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/517 (2013.01); C07D 239/84 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 491/107 (2013.01); C07F 9/65583 (2013.01);
Abstract

Fused pyrimidine compounds as kinase inhibitors, such as multi-kinase inhibitors, are provided. Fused pyrimidine compounds as IGF-IR inhibitors are provided. Fused pyrimidine compounds that are inhibitors of Trk receptors (e.g., Trk A, Trk B and Trk C) are provided also. The compounds may be used in a method of treating cancer. Pharmaceutical compositions containing a fused pyrimidine compound and a pharmaceutically acceptable carrier are also provided, as are kits containing a fused pyrimidine compound or salt thereof and instructions for use, e.g., in a method of treating cancer.


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