The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Oct. 04, 2013
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Donald R. Kirsch, Bedford, MA (US);
Radhia Benmohamed, Tewksbury, MA (US);
Anthony C. Arvanites, Medford, MA (US);
Richard I. Morimoto, Evanston, IL (US);
Guoyao Xia, Chicago, IL (US);
Richard B. Silverman, Winnetka, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/62 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
C07D 239/62 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01);
Abstract
The present invention relates to the identification of inventive pyrimidine-2,4,6-triones (PYT compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the inventive PYT compounds.