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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9499480 B1

PDFFull Text
Date of Patent:
Nov. 22, 2016

Filed:

Apr. 07, 2014

Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid

Applicant:

Bhi Limited Partnership, Laval, Quebec, CA;

Inventors:

Xianqi Kong, Dollard-des-Ormeaux, CA;

Mohamed Atfani, Laval, CA;

Benoit Bachand, St-Laurent, CA;

Abderrahim Bouzide, Laval, CA;

Stephane Ciblat, Montreal, CA;

Sophie Levesque, Mirabel, CA;

David Migneault, Laval, CA;

Isabelle Valade, Laval, CA;

Xinfu Wu, Laval, CA;

Daniel Delorme, St-Lazare, CA;

Assignee:

BHI Limited Partnership, Laval, Quebec, CA;

Attorney:

Cooley LLP

Primary Examiner:

Jonathan S Lau

Int. Cl.
CPC ...
C07D 285/36 (2006.01); C07D 323/02 (2006.01); C07D 285/38 (2006.01); C07D 333/24 (2006.01); C07D 217/24 (2006.01); C07D 291/02 (2006.01); C07D 233/64 (2006.01); C07D 209/20 (2006.01); C07K 5/068 (2006.01); C07K 5/062 (2006.01); C07C 309/24 (2006.01); A61K 47/48 (2006.01); C07C 309/19 (2006.01); C12P 13/00 (2006.01); C07C 309/18 (2006.01); C07H 15/12 (2006.01); C07H 7/02 (2006.01); C07J 9/00 (2006.01); C12P 11/00 (2006.01); C07C 309/15 (2006.01); C07K 5/083 (2006.01); C07D 207/16 (2006.01);
U.S. Cl.
CPC ...
C07C 309/24 (2013.01); A61K 47/48023 (2013.01); A61K 47/48092 (2013.01); C07C 309/15 (2013.01); C07C 309/18 (2013.01); C07C 309/19 (2013.01); C07D 207/16 (2013.01); C07D 209/20 (2013.01); C07D 217/24 (2013.01); C07D 233/64 (2013.01); C07D 285/36 (2013.01); C07D 285/38 (2013.01); C07D 291/02 (2013.01); C07D 323/02 (2013.01); C07D 333/24 (2013.01); C07H 7/02 (2013.01); C07H 15/12 (2013.01); C07J 9/005 (2013.01); C07K 5/0606 (2013.01); C07K 5/06026 (2013.01); C07K 5/06052 (2013.01); C07K 5/06069 (2013.01); C07K 5/06086 (2013.01); C07K 5/081 (2013.01); C07K 5/0806 (2013.01); C12P 11/00 (2013.01); C12P 13/001 (2013.01);
Abstract

The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compound that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to the prevention and treatment of Alzheimer's disease.

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